Born in New Hartford, Connecticut on July 29, 1803, David Lyman graduated from Andover Theological Seminary. The American Board of Commissioners for Foreign Missions (ABCFM), based in Boston, ordained him as a minister in 1831. Months later he married Sarah Joiner of Royalton, Vermont. After an ocean voyage of 173 days, the couple arrived at Honolulu, Hawaiʻi on May 17, 1832. They had eight children in Hilo where he served as a preacher, teacher, principal, and government official. He lived the rest of his life in the town.